Published Research Highlights of 2001

Clinical implications of cross-reactive food allergens 
Sicherer SH 
Jaffe Food Allergy Institute, Division of Allergy and Immunology, Department of Pediatrics, Mount Sinai School of Medicine, New York, NY 
J Allergy Clin Immunol 2001;108(6):881-90 
The article highlighted several points, among them: 1) some food families are very cross reactive (tree nuts, fish, shellfish, mammal milk) while others are not (beans, legumes, grains), and 2) allergy tests are often positive for related foods (e.g., a positive test for string bean in someone allergic to peanut) but true allergic reactions when eating the related food (in this case string bean) are comparatively uncommon. 
View abstract.

Detection of peanut allergens in breast milk of lactating women 
Vadas P, Wai Y, Burks W, Perelman B 
Division of Allergy and Clinical Immunology, St Michael's Hospital, Toronto, Ontario, Canada 
Journal of the American Medical Association 2001;285(13):1746-8 
Investigators studied 23 lactating women, ages 21 to 35, to determine if maternal ingestion of peanut protein causes the protein to pass into breast milk during lactation. The women were given 50 g of dry roast peanuts and afterwards samples of breast milk were collected hourly. Investigators detected peanut protein in 11 women. 
View abstract.

Effects of cooking methods on peanut allergenicity 
Beyer K, Morrow E, Li XM, Bardina L, Bannon GA, Burks AW, Sampson HA 
The Mount Sinai School of Medicine, New York, NY 
J Allergy Clin Immunol 2001;107(6):1077-81 
Although China has a high rate of peanut consumption, the prevalence of peanut allergy in this country is lower than in the United States. This study examined whether the method of preparing peanuts could be a factor in allergy prevalence between these two countries. It was discovered that frying or boiling peanuts, as practiced in China, reduces the allergenicity of peanuts, as opposed to the dry roasting method commonly practiced in the United States. 
View abstract.

Epinephrine dispensing for the out-of-hospital treatment of anaphylaxis in infants and children: a population-based study 
Simons FE, Peterson S, Black CD 
Department of Pediatrics & Child Health, Faculty of Medicine, University of Manitoba, Winnipeg, Canada 
Annals of Allergy, Asthma & Immunology 2001;86(6):622-6 
This study examined the prescription patterns over 4 years for to a population of 279,638 infants, children, and adolescents (up to but not including the 17th birthday). It was discovered that epinephrine was dispensed for 3,340 children (1.2% of the pediatric population). Of all epinephrine formulations, EpiPen Jr was prescribed 38.6% of the time compared to EpiPen (57.4%). 
View abstract.

Identification of IgE- and IgG-binding epitopes on alpha(s1)-casein: differences in patients with persistent and transient cow's milk allergy 
Chatchatee P, Jarvinen KM, Bardina L, Beyer K, Sampson HA 
Division of Pediatric Allergy & Immunology and the Jaffe Institute for Food Allergy, The Mount Sinai School of Medicine, New York, NY 
J Allergy Clin Immunol 2001;107(2):379-83 
This study showed that casein, the major allergen in milk accounting for 80% of the protein, plays an important role in persistent cow milk allergy. Scientists found that older children and adults who are milk allergic have higher levels of casein-specific IgE antibodies than do younger children. The study suggests that doctors may be able to screen for specific IgE antibodies to portions of the caseins to determine if a child is likely to outgrow his or her milk allergy. Those who are not likely to outgrow the allergy may be considered for immunotherapy, when it becomes available. 
View abstract.

School readiness for children with food allergies 
Rhim GS, McMorris MS 
University of Michigan Medical Center, Division of Allergy, Ann Arbor, MI 
Annals of Allergy, Asthma & Immunology 2001;86(2):172-6 
This study sought to identify Michigan school awareness of food allergy, and prevention and treatment policies for students who have food allergies. A questionnaire to asses these areas was mailed to 2,082 public elementary school principals. 
View abstract.

The natural history of peanut allergy 
Skolnick HS, Conover-Walker MK, Koerner CB, Sampson HA, Burks W, Wood RA 
Department of Pediatrics, Johns Hopkins University, Baltimore, MD 
J Allergy Clin Immunol 2001;107(2):367-74 
Investigators evaluated 233 patients with peanut allergy, ages 4 to 20, to determine how many of them outgrow their allergy, and found that approximately 21.5% of patients outgrow a peanut allergy. 
View abstract.

 

Disclaimer and Limitation of Liability

The Food Allergy & Anaphylaxis Network serves only as a point of contact for the research projects listed on this web page. The Food Allergy & Anaphylaxis Network does not endorse and is not affiliated in any other way with these research projects, unless otherwise noted. The Food Allergy & Anaphylaxis Network makes no promises or warranties, expressed and implied, as to the appropriateness of any given research project listed on this Web site. The Food Allergy & Anaphylaxis Network disclaims all warranties of fitness for a particular purpose and merchantability as to all such matters. The Food Allergy & Anaphylaxis Network will not be liable under any circumstances for any damages arising from participation in any of the research projects listed on this Web site, whether such losses are special, incidental, consequential, or otherwise.

E-Mail Print Bookmark and Share